Holland, Cam,Kehoe, John,Snyder, Linda,Sepulveda, Alejandro,Villareal, Daniel
申请号:
AU2017229575
公开号:
AU2017229575A1
申请日:
2017.03.08
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Provided herein are antibodies that specifically bind to GITR. Also described are related polynucleotides capable of encoding the provided GITR-specific antibodies or antigen-binding fragments, cells expressing the provided antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled antibodies or antigen-binding fragments. In addition, methods of using the provided antibodies are described. For example, the provided antibodies may be used to enhance an immune response in a subject against cancer.