The present disclosure provides a benzene fused heterocyclic compound of Formula (I):Formula (I), whereinis a single or double bond； n is 0 or 1； X is -CH2-, O, NR1, or S； A is -C(Ra1)(Ra2)(Ra3) or -N(Ra1)(Ra2), wherein Ra1, Ra2and Ra3are independently selected from a group consisting of: H, alkyl, cycloalkyl, heterocyclic alkyl, aryl, heteroaryl, C1-C3hydrocarbon, -RaaORbb, -C(O)ORaaRbb, -C(O)RaaRbb, -C(O)NRaaRbb, -SO2RaaRbband -SO2NRaaRbbwhich are optionally substituted by at least one substituent independently selected from a group consisting of: alkyl, cycloalkyl, heterocyclic alkyl, aryl, -Ybb, -ArbbYbb, -ORcc, and -OArbbYbb, wherein Raa, Rbband Rccindependently are nil, H, halogen, alkyl, or aryl, Ybbis CN or halogen, and Araaand Arbbindependently are aryl or heteroaryl； R1is H or alkyl； R2is alkyl, cycloalkyl, heterocylic alkyl, aryl, heteroaryl, C1-C6hydrocarbon optionally substituted by at least one substituent independently selected from a group consisting of: -R2aOR2b, -R2aC(O)OR2bR2c, -R2aC(O)R2bR2c, -R2aC(O)NR2bR2c, -R2aNR2bC(O)NR2cR2d, -R2aNR2bC(O)R2cR2d, -R2aNR2bC(O)OR2cR2d, -R2aSO2R2bR2c, -R2aNR2bSO2NR2cR2dand -R2aSO2NR2bR2c, optionally substituted by at least one substituent independently selected from a group consisting of alkyl, cycloalkyl, heterocyclic alkyl, heteroaryl, and aryl, wherein R2a, R2b, R2cand R2dare independently selected from nil, H, halogen, alkyl, cycloalkyl, heterocyclic alkyl, heteroaryl, aryl or C1-C6hydrocarbons, optionally substituted by at least one substituent independently selected from a group consisting of -OR2e, =O, =S, -SO2R2e, -SO2NR2eR2f, -NR2gSO2NR2eR2f, -NR2gC(O)NR2eR2f, -C(O)NHR2e, -NHC(O)R2e, -NHC(O)OR2e, -NO2, -CO2R2eand -C(O)R2e, wherein R2e, R2f, and R2gindependently are H or alkyl.本揭露提供一式(I)苯並雜環化合物：式(I)， 其中為單鍵或雙鍵；n為0或1；X為-CH2-、O、NR1、或S；A為-C(Ra1)(Ra2)(Ra3)或-N(Ra1)(Ra2)，其中Ra1、Ra2、及Ra3係獨立地選自於由：氫、烷基、環烷基、雜環烷基、芳基、雜芳基、C1-C3烴、-RaaORbb、-C(O)ORaaRbb、-C(O)RaaRbb、-C(O)NRaaRbb、-SO2RaaRbb、及-SO2NRaaRbb組成之群組，其可選擇地經至少一取代基取代，該
