SMUTNEY, CHAD C.,KINSEY, P. SPENCER,SAHI, CARL R.,ADAMO, BENOIT,POLIDORO, JOHN M.,MCLEAN, SCOTT,OVERFIELD, DENNIS O.,BRYANT, ANTHONY J.,HE, TOM,MANN, ALFRED
申请号:
CA2728230
公开号:
CA2728230C
申请日:
2009.06.12
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
A breath-powered, dry powder inhaler(100), a cartridge (150), and a pulmonary- drug deliverysystem are provided. The dry powder inhaler (100) can beprovided with or without a unit dose cartridge (150) forusing with the inhaler (100). The inhaler (100) and/or cartridge(150) can be provided with a drug delivery formulationcomprising, for example, a diketopiperazine and anactive ingredient, including, peptides and proteins such asinsulin and glucagon-like peptide 1 for the treatment ofdiabetes and/or obesity. The dry powder inhaler (100) iscompact; can be provided in various shapes and sizes, colors,and comprises a housing (120), a mouthpiece (130), acartridge placement area, and a mechanism for openingand closing the medicament cartridge. The device is easyto manufacture, provides a pre-metered single unit dose, itis relatively easy to use, and can be reusable or disposable.