SMUTNEY, CHAD C.,KINSEY, P. SPENCER,SAHI, CARL R.,ADAMO, BENOIT,POLIDORO, JOHN M.,MCLEAN, SCOTT,OVERFIELD, DENNIS O.,BRYANT, ANTHONY J.,HE, TOM,MANN, ALFRED
申请号:
CA2982550
公开号:
CA2982550C
申请日:
2009.06.12
申请国别(地区):
CA
年份:
2020
代理人:
摘要:
A breath-powered, dry powder inhaler (100), a cartridge (150), and a pulmonary- drug delivery system are provided. The dry powder inhaler (100) can be provided with or without a unit dose cartridge (150) for using with the inhaler (100). The inhaler (100) and/or cartridge (150) can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. The dry powder inhaler (100) is compact; can be provided in various shapes and sizes, colors, and comprises a housing (120), a mouthpiece (130), a cartridge placement area, and a mechanism for opening and closing the medicament cartridge. The device is easy to manufacture, provides a pre-metered single unit dose, it is relatively easy to use, and can be reusable or disposable.