KHLEIF, SAMIR,MKRTICHYAN, MIKAYEL,LEBEDYEVA, IRYNA,ALBERS, THOMAS
申请号：
CA3045759
公开号：
CA3045759A1
申请日:
2017.12.01
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Several compounds have been discovered that modulate signal transduction through the PD-1 receptor. In certain embodiments, the compounds promote or induce an activating signal through the PD-1 receptor that activates a T cell. The compounds can bind to PD-1 and inhibit or prevent ligands from binding to PD-1 and thereby suppress inhibitory signal transduction through the PD-1 receptor.
