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PROCEDE DE PREPARATION STEREOSELECTIVE DE (-)-HALOFENATES ET D'INTERMEDIAIRES DE CES DERNIERS
专利权人:
METABOLEX; INC.
发明人:
ZHU, YAN,CHENG, PENG,CHEN, XIN,MA, JINGYUAN,ZHAO, ZUCHUN
申请号:
CA2623350
公开号:
CA2623350C
申请日:
2006.09.21
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention provides a compounds the formula (IV): and methods forproducing an .alpha.-(phenoxy)phenylacetic acid compound of the formula:wherein R1 is a member selected from the group consisting of: each R2 is amember independently selected from the group consisting of (C1- C4)alkyl,halo, (C1-C4)haloalkyl, amino, (C1-C4 aminoalkyl, amido, (C1- C4)amidoalkyl,(C1-C4)sulfonylalkyl, (C1-C4)sulfamylalkyl, (C1-C4)allcoxy, (C1-C4)heteroalkyl, carboxy and nitro; the subscript n is 1 when R1 has theformula (a) or (b) and 2 when R1 has the formula (c) or (d); the subscript mis an integer of from O to 3; * indicates a carbon which is enriched in onestereoisomeric configuration; and the wavy line indicates the point ofattachment of R1; and compounds .
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