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Sposób stereoselektywnego wytwarzania (-)-halofenatu i jego półproduktów
专利权人:
Cymabay Therapeutics; Inc.
发明人:
ZHU, YAN,CHENG, PENG,CHEN, XIN,MA, JINGYUAN,ZHAO, ZUCHUN
申请号:
PL06815150
公开号:
PL1940387T3
申请日:
2006.09.21
申请国别(地区):
PL
年份:
2013
代理人:
摘要:
The present invention provides a compounds the formula (IV): and methods for producing an α-(phenoxy)phenylacetic acid compound of the formula: wherein R1 is a member selected from the group consisting of: each R2 is a member independently selected from the group consisting of (C1-C4)alkyl, halo, (C1-C4)haloalkyl, amino, (C1-C4)aminoalkyl, amido, (C1-C4)amidoalkyl, (C1-C4)sulfonylalkyl, (C1-C4)sulfamylalkyl, (C1-C4)alkoxy, (C1-C4)heteroalkyl, carboxy and nitro; the subscript n is 1 when R1 has the formula (a) or (b) and 2 when R1 has the formula (c) or (d); the subscript m is an integer of from 0 to 3; * indicates a carbon which is enriched in one stereoisomeric configuration; and the wavy line indicates the point of attachment of R1; and compounds.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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