System for the irradiation of a target material Capsule for the transfer of a target material (2) in a conveying system between a target irradiation station and a collecting station, such as a hot cell, comprising: - a beamline channel (4) for the passage of an energetic beam irradiating said target material (2), - a target holder (1) for holding the target material (2) or a substrate backing the target material (2), - a housing (3) for enclosing said target holder (1), said housing being openable such that the target material (2) can be inserted in or removed from the target holder (1) when the housing (3) is opened, - a degrader foil (5a, 5b, 5c), said degrader foil being positioned across the beamline channel (4), - at least one target cooling inlet (14) and one target cooling outlet (15), - at least one degrader foil cooling inlet (20) and one degrader foil cooling outlet (21).