Method for producing a bone prosthesis, comprising forming a surgical guide(1) equipped with at least one artificial prosthesis (15) and with at least a firsthole passing through each artificial prosthesis in a predetermined orientation,placing the surgical guide on a model (2), drilling a second hole (16) throughthe model with the aid of a drill (8) passed through each first hole, the passageof the drill through the corresponding first hole taking place without contacttherewith, and guiding the drill in said predetermined orientation with theaid of drill introduction means (10, 11) situated outside said first hole.