PROBLEM TO BE SOLVED: To provide methods for the treatment of sickle cell disease, acute chest syndrome, peripheral arterial disease, myocardial infarction, cerebral apoplexy, peripheral vascular disease, macular degeneration, multiple organ failure, ischemia, hemorrhagic shock, septic shock, acidosis, hypothermia, anemic decomposition, surgery, injury, acute blood loss, and blood disease, by improving oxygenation by damaged erythrocytes.SOLUTION: THE invention relates to a method comprising a) mixing blood or a red blood cell heavy solution with specific polyoxyethylene/polyoxypropylene copolymer to produce a transfusion composition； and b) storing the transfusion composition, and improving the safety and efficacy of a transfusion blood or the red blood cell heavy solution. The copolymer is a triblock copolymer represented by the formula: HO(CHO)-(CHO)-(CHO)H [where, b is an integer such that the hydrophobic portion represented by (CHO) has a molecular weight of 950-4000； and a is an integer such that the hydrophilic portion represented by (CHO) constitutes 50-90% by weight of the copolymer.]SELECTED DRAWING: None【課題】ダメージを受けた赤血球によるオキシジェネーションを改善する、鎌状赤血球病、急性胸部症候群、末梢動脈疾患、心筋梗塞、脳卒中、末梢血管疾患、黄斑変性、多臓器不全、虚血、出血性ショック、敗血性ショック、アシドーシス、低体温症、貧血性分解、手術、外傷、急性血液喪失、及び血液疾患の治療方法の提供。【解決手段】ａ）血液又は赤血球濃厚液と、特定のポリオキシエチレン／ポリオキシプロピレン共重合体とを混合し輸液用組成物を生成し、ｂ）前記輸液用組成物を貯蔵する、輸液用の血液又は赤血球濃厚液の安全性及び有効性を改善する方法。前記共重合体が式：ＨＯ（Ｃ２Ｈ４Ｏ）ａ－（Ｃ３Ｈ６Ｏ）ｂ－（Ｃ２Ｈ４Ｏ）ａＨ［ｂは（Ｃ３Ｈ６Ｏ）で表され疎水性部分の分子量が９５０～４０００となる整数；ａは（Ｃ２Ｈ４Ｏ）で表される親水性部分が共重合体の５０～９０重量％の構成となる整数］で表されるトリブロック共重体である方法。【選択図】なし
