Jong Hwan Kwak,Kyung Bok Lee,Jong-Hwan Park,Dong Hee Na,Seok-Joon Kwon,Robert J. Linhardt,Jonathan S. Dordick,Fuming Zhang
申请号：
US15679709
公开号：
US20180050056A1
申请日:
2017.08.17
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided are a conjugate including a core and sialic acids or derivatives thereof bound to the surface of the core, and use thereof. The conjugate provided in the present invention binds with hemagglutinin on the surface of influenza virus to inhibit the course of infection of influenza virus, thereby preventing or treating infection of influenza virus and also preventing or treating infection of influenza virus resistant to antiviral agents. Accordingly, the conjugate may be widely used in the development of prophylactic or therapeutic agents for influenza virus infection.
