COMPOUND AND PHARMACEUTICALLY ACCEPTABLE SALTS OF THE SAME, PROCESS, FORMULATION OF AEROSOL, METHOD FOR PREVENTION AND TREATMENT OF PULMONARY INFLAMMATION, AND USE OF A COMPOUND.
WILLIAM R. BAKER,MARCIN STASIAK,SUNDARAMOORTHI SWAMINATHAN,MUSONG KIM
申请号：
BRPI0720032
公开号：
BRPI0720032A2
申请日:
2007.12.12
申请国别(地区):
BR
年份:
2013
代理人:
摘要：
A mutual prodrug of an AISTM and a &bgr；-agonist in formulation for delivery by aerosolization to inhibit pulmonary inflammation and bronchoconstriction is described. The mutual prodrug is preferably formulated in a small volume solution (10-500 &mu；L) dissolved in a quarter normal saline having pH between about 5.0 and 7.0 for the treatment of respiratory tract inflammation and bronchoconstriction by an aerosol having mass median average diameter predominantly between about 1 to 5&mu；, produced by nebulization or by dry powder inhaler.
