COMPOSITIONS PEPTIDIQUES ET MÉTHODES DE TRAITEMENT D'UNE LÉSION PULMONAIRE, DE L'ASTHME, DE L'ANAPHYLAXIE, D'UN DÈME DE QUINCKE, DE SYNDROMES DE PERMÉABILITÉ VASCULAIRE SYSTÉMIQUE ET D'UNE CONGESTION NASALE
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
发明人:
KOMAROVA, YULIA, A.,SAQIB, UZMA,VOGEL, STEPHEN, M.,MALIK, ASRAR, B.
申请号：
EP12800251
公开号：
EP2717897A4
申请日:
2012.06.13
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
Provided herein are peptide inhibitors of the interaction between End Binding Protein 3 (EB3) and Inositol 1,4,5-Trisphosphate Receptor Type 3 (IP3R3). Also provided are methods and materials for treating lung injury, including acute lung injury, which may include hyperpermeability of lung vessels, vascular leakage, the development of edema, asthma, anaphylaxis, angioedema, systemic vascular permeability syndromes, and nasal congestion.
