COMPOSITIONS PEPTIDIQUES ET METHODES DE TRAITEMENT D'UNE LESION PULMONAIRE, DE L'ASTHME, DE L'ANAPHYLAXIE, D'UN ƒ；DEME DE QUINCKE, DE SYNDROMES DE PERMEABILITE VASCULAIRE SYSTEMIQUE ET D'UNE CONGESTION NASALE
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
发明人:
KOMAROVA, YULIA A.,SAQIB, UZMA,VOGEL, STEPHEN M.,MALIK, ASRAR B.
申请号：
CA2838662
公开号：
CA2838662C
申请日:
2012.06.13
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Provided herein are peptide inhibitors of the interaction between End Binding Protein 3 (EB3) and Inositol 1,4,5-Trisphosphate Receptor Type 3 (IP3R3). Also provided are methods and materials for treating lung injury, including acute lung injury, which may include hyperpermeability of lung vessels, vascular leakage, the development of edema, asthma, anaphylaxis, angioedema, systemic vascular permeability syndromes, and nasal congestion.
