As for this invention, temporarily blood impermeability in order to achieve the discharge of the inner split growth of the organization which is improved and remedy, it is something which offers the production method of the ePTFE material which can transplant, the said method, includes process, the process which fills the said biodegradation characteristic hydrogel seal medicine, to the said ePTFE material, and hardens the said ePTFE material the process which produce the biodegradation characteristic hydrogel seal medicine which includes also process and the remedy medicine which manufacture the ePTFE material which has, the average internode distance of the range which reaches 60 - 200 millimicrons.本発明は、改善された組織の内方成長及び治療薬の放出を達成するための、一時的に血液不透過性の、移植することのできるePTFE材料の製造方法を提供するものであり、該方法は、60~200μmなる範囲の、平均節間距離を持つePTFE材料を調製する工程、治療薬剤をも含む生分解性のヒドロゲル封止剤を製造する工程、該生分解性のヒドロゲル封止剤を、該ePTFE材料に注入する工程、及び該ePTFE材料を硬化する工程を含む。
