SHIMADA, KOUSEI,ONISHI, YOSHIYUKI,MORI, MAKOTO,TOKUMARU, ERI
申请号:
ES08739652
公开号:
ES2550479T3
申请日:
2008.04.02
申请国别(地区):
ES
年份:
2015
代理人:
摘要:
A compound having the general formula (I): ** Formula ** in which R1 represents a C6-C10 aryl group that may be substituted with between 1 and 5 groups independently selected from the Substituent Group a, or a heterocyclic group which may be substituted with between 1 and 3 groups independently selected from the Substituent Group a, R2 represents a C1-C6 alkyl group, R3 represents a C6-C10 aryl group which may be substituted with between 1 and 5 groups independently selected from the Substituent Group a, Q represents a group represented by the formula>; = CH- or a nitrogen atom, and Substituent Group a represents a group consisting of a halogen atom, a C1-C6 alkyl group, a C1- hydroxyalkyl group C6, a halogenated C1-C6 alkyl group, a carboxyl group, a carbamoyl group, a C2-C7 alkylcarbonyl group, a C2-C7 alkoxycarbonyl group, a hydroxy group, a C1-C6 alkoxy group, a halogenated C1-C6 alkoxy group , one GR C2-C7 alkylcarbonyloxy, a C2-C7 alkoxycarbonyloxy group, an amino group, a C2-C7 alkylcarbonylamino group, a C2-C7 alkoxycarbonylamino group, a C1-C6 alkylsulfonylamino group, a 4- morpholinyl group and a di- (alkyl) group C1-C6) amino] or a pharmacologically acceptable salt thereof.Un compuesto que tiene la fórmula general (I):**Fórmula** en la que R1 representa un grupo arilo C6-C10 que puede estar sustituido con entre 1 y 5 grupos seleccionados independientemente de entre el Grupo Sustituyente a, o un grupo heterocíclico que puede estar sustituido con entre 1 y 3 grupos seleccionados independientemente de entre el Grupo Sustituyente a, R2 representa un grupo alquilo C1-C6, R3 representa un grupo arilo C6-C10 que puede estar sustituido con entre 1 y 5 grupos seleccionados independientemente de entre el Grupo Sustituyente a, Q representa un grupo representado por la fórmula >;=CH-o un átomo de nitrógeno, y Grupo Sustituyente a representa un grupo que consiste en un átomo de halógeno, un grupo alquilo C1-C6, un grupo hidroxialquilo C1-C6, un grupo alquilo C1-C6