Jason Richard Betley,James Christopher Pearson,Helen Rosemary Tatton,Ben Martin Beacom
申请号:
US11917053
公开号:
US08501939B2
申请日:
2006.06.08
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compounds of the general formula (I): in which inter alia Q1 represents —NR1R3, —OR1 or —SR1 and Q2 represents —NR2R4, —OR2 or —SR2, and A represents the point of attachment to a support matrix, are useful as protein binding ligands when (a) at least one of R1, R2, R3 and R4 includes an alkyl group —CnH2n+1 in which n is greater than or equal to 7 (b) at least two of R1, R2, R3 and R4 independently include an alkyl group —CnH2n+1 or a cycloalkyl group —CnH2n−1 in which n is greater than or equal to 4 or (c) at least three of R1, R2, R3 and R4 independently include a C1-12 alkyl group substituted by —NR5R6 or aryl.