REZA OLIYAI,TERRENCE C. DAHL,MARK M. MENNING,TAIYIN YANG,MUNIR A. HUSSAIN,ROBERT A. LIPPER,ROBERT L. JERZEWSKI
申请号:
PT11167101
公开号:
PT2386294E
申请日:
2006.06.13
申请国别(地区):
PT
年份:
2015
代理人:
摘要:
In accordance with this invention a novel pharmaceutical product containing efavirenz, emtricitabine and tenofovir DF are provided as a multicomponent unitary oral dosage form, component 1 comprising tenovofir DF (and, optionally, emtricitabine) and component 2 comprising efavirenz, wherein components 1 and 2 are in a stabilizing configuration. In preferred embodiments component 1 is made by dry granulation. In another embodiment a composition comprising tenovofir DF and a surfactant is claimed.