Pharmaceutical unit dosage form comprising tenofovir DF, emtricitabine, efavirenz, and a surfactant,

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专利权人:

BRISTOL-MYERS SQUIBB & GILEAD SCIENCES; LLC

发明人:

DAHL, TERRENCE, C.,HUSSAIN, MUNIR, A.,LIPPER, ROBERT, A.,JERZEWSKI, ROBERT, L.,MENNING, MARK, M.,OLIYAI, REZA,YANG, TAIYIN

申请号：

DK11167101

公开号：

DK2386294T3

申请日:

2006.06.13

申请国别(地区):

DK

年份:

2015

代理人:

摘要：

In accordance with this invention a novel pharmaceutical product containing efavirenz, emtricitabine and tenofovir DF are provided as a multicomponent unitary oral dosage form, component 1 comprising tenovofir DF (and, optionally, emtricitabine) and component 2 comprising efavirenz, wherein components 1 and 2 are in a stabilizing configuration. In preferred embodiments component 1 is made by dry granulation. In another embodiment a composition comprising tenovofir DF and a surfactant is claimed.

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http://www.ckcest.cn/home/