Yong-Xin Li,Neil J. Poloso,John E. Donello,Qianyong Liu
申请号：
US16634532
公开号：
US20200171026A1
申请日:
2018.07.27
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Prostacyclin (PGI2) analogues which are agonists of the prostacyclin receptor (PI) are demonstrated to activate lipolytic activity in adipocytes. Also described are pharmaceutical compositions and methods for using the PGI2 receptor agonists to reduce subcutaneous adipose tissue and to treat or reduce symptoms of obesity-related diseases or disorders such as diabetes mellitus, fatty liver disease and cardiovascular disease.
