JAMES D. RODGERS,ANDREW P. COMBS,RICHARD B. SPARKS,TOMAS P. JR. MADUSKUIE
申请号：
ARP140101029
公开号：
AR095326A1
申请日:
2014.03.14
申请国别(地区):
AR
年份:
2015
代理人:
摘要：
1. Characteristic 1: a formula compound (1) or a salt acceptable in medicine, the characteristic of which is: - 8315； - 8315； - 8315； - 8315； - 8315； - 8315； - represents a simple connection or double connection； L is Cr 8313； - r8313；； 7491；O S SO o SOCy1 is selected from the heteromorphic group composed of phenyl or 5-6 members composed of carbon and 1, 2, 3 or 4 heteromorphic atoms selected from n, O and s, among which 5-6 members of cy1 may choose to be replaced by 1, 2, 3 or 4 groups selected from R1 independently；R1 and R2 are independent of H, halo, CN, oh, lease c833213126,C₂₋₆ alkenyl,1. C 83228331 asphalt；haloalkyl C₁₋₆,ORᵃ¹,SRᵃ¹,C (3DO) RC (3DO) NR RC (3DO) OROC (3DO) ROC (3DO) NR RNR RNR C (3DO) RNR C (3DO) NR RNR C (3DO) ORS (3DO) RS (3DO) NR RS (3DO) RNr7580801； s (= O) 8322；； r74955；； 1 and S (= O) 8322；； nr7580808； - sr7496；； 1,where the alkyl C₁₋₆,C₂₋₆ alkenyl,and C₂₋₆ alkynyl of R¹ and R² are optionally substituted with 1, 2, or 3 groups independently selected from halo, CN, OH, ORᵃ¹,SRᵃ¹,C (3DO) RC (3DO) NR RC (3DO) OROC (3DO) ROC (3DO) NR RNR RNR C (3DO) RNR C (3DO) NR RNR C (3DO) ORS (3DO) RS (3DO) NR RS (3DO) RNR 7580801； (= O) 8322；； r74955；； 1 and S (= O) 8322；； nr7580808； - sr7496；； 1；1. If R1 or R2 is not Cl, Br, I, CN, or Wu at L or s, or R1 and R2 are combined with the carbon atoms attached to them to form a cyclo-c833238327；wherein the cycloalkyl group is optionally substituted with 1, 2, 3, or 4 groups independently selected from R²⁰；Cy3 from phenyl, cycloquilo c83231；a 5-10 membered heteroaryl group comprising carbon and 1, 2, 3 or 4 heteroatoms selected from N, O and S, and a 4-10 membered heterocycloalkyl group comprising carbon and 1, 2, or 3 heteroatoms selected from N, O and S, where phenyl, C₃₋₇ cycloalkyl,Heterosexuality of 5-10 members and heterosexuality of 4-10 Cy3 members can be replaced by 1, 2, 3 or 4 independent R1 target groups,wherein a 5-10 membered heteroaryl group ring-forming nitrogen atom or a 4-10 membered heteroc
