Carriero, Maria Vincenza,Pavone, Vincenzo,De Rosa, Mario
申请号：
AU2007283150
公开号：
AU2007283150B2
申请日:
2007.07.19
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
Peptides and their functionally equivalent derivatives, in salified or non-salified form, with the general formula L-XX-X-X, wherein: L is H, or acyl, or any natural or non-natural amino acid, optionally N-acylated, N-alkylated and/or Cα-alkylated； X and X, which are equal or different, are any natural or non-natural basic amino acid, optionally N-alkylated and/or Cα-alkylated； X is any natural or non-natural amino acid, optionally N-alkylated and/or Cα-alkylated, with the proviso that it is not glycine and amino acids mono-substituted on the α carbon atom with a linear or cyclic alkyl group, from 1 to 10 carbon atoms, and amino acids mono-substituted on the α carbon atom with a linear or cyclic alkyl group containing 4 to 10 carbon atoms, or amino acids mono-substituted on the α carbon atom with an alkyl group containing 1 to 8 carbon atoms, optionally substituted with a carbamoyl, hydroxyl or aromatic group； X is any natural or non-natural hydrophobic amino acid, optionally Cα-alkylated and/or amidated at the C-terminal end, or any hydrophobic amino alcohol, or a hydrophobic -diamine, optionally N'-alkylated or N'-acylated.
