The present invention relates to an antioxidant composition, and more particularly, to an antioxidant composition containing an extract of Tetrahedronate as an active ingredient or a fraction thereof, and to a useful material (substance) which can be added to medicines, cosmetics, foods, animal feeds and the like. The present invention also relates to a pharmaceutical composition for preventing or treating eye diseases, a food composition for improving eye diseases, and a health functional food comprising an extract of Tooth mothballs or a compound isolated therefrom as an active ingredient. The Sargassum serratifolium extract or its fractions according to the present invention have excellent DPPH radical scavenging activity, ABTS cation scavenging activity and hydroxy radical (-OH) scavenging activity in addition to intracellular nitric oxide and reactive oxygen species scavenging ability, The composition containing the compound as an active ingredient is useful as a functional additive for pharmaceuticals, cosmetics, foods, animal feeds and the like as a composition having an antioxidative activity. In addition, the Sargassum serratifolium extract according to the present invention or a compound derived therefrom is excellent in protecting photoreceptor cells present in the retina of the eye, As a composition for prevention, improvement or treatment, it can be usefully used as a material for medicines and health functional foods. In particular, since the sawtooth moth is edible as a natural substance, the composition of the present invention comprising extracts derived therefrom and fractions or compounds derived therefrom has a safety advantage for long-term use.본 발명은 항산화 조성물에 관한 것으로, 더욱 자세하게는 유효성분으로서 톱니모자반 추출물 또는 이의 분획물을 포함하는 항산화 조성물로 의약품, 화장품, 식품, 동물사료 등에 첨가하여 사용될 수 있는 유용한 소재(물질)에 관한 것이다. 또한 본 발명은, 톱니모자반 추출물 또는 이로부터 분리한 화합물을 유효성분으로 포함하는 안 질환 예방 또는 치료용 약제학적 조성물, 안질환 개선용 식품 조성물 및 건강기능식품에 관한 것이다. 본 발명에 따른 톱니모자반(Sargassum serratifolium) 추출물 또는 이의 분획물은 세포 내 산화질소 및 활
