The new creation is a liposome structure that can improve the percutaneous absorption of effective components, which consists of an inner outer system: an elite core, its system contains effective components, and a liposome protective layer, which has a hydrophilic orientation toward the inner surface of the essence core and a hydrophilic far from the outer surface of the essence core, and between the inner surface and the outer surface. It has a hydrophobic region.The liposome structure can improve the transdermal absorption rate of the active ingredient, make the active ingredient quickly and completely enter the skin, absorb and play a role through the skin tissue, and then use a small amount of the active ingredient to achieve the same or better effect.本新型創作係關於一種可改善有效成分之經皮吸收率的脂質體結構,其由內而外係包含:一精華核心,其係包含有效成分;以及一脂質體保護層,其具有一親水性之朝向精華核心的內側表面與一親水性之遠離精華核心的外側表面,且在該內側表面與該外側表面之間具有一疏水性區域。本脂質體結構能夠提升有效成分之經皮吸收率,使得有效成分快速完整進入皮膚,經由皮膚組織吸收並發揮作用,進而可以使用較少量的有效成分即達成相同或更佳的功效。