ALSINA-FENANDEZ JORGE,GUO LILI,BOKVIST KRISTER BENGT,MAYER JOHN PHILIP
申请号：
ZA201206832
公开号：
ZA201206832B
申请日:
2012.09.12
申请国别(地区):
ZA
年份:
2014
代理人:
摘要：
The present invention is in the field of treatment of diabetes and relates to peptides that exhibit activity for both glucose-dependent insulinotropic peptide receptor (GIP-R) and glucagon-like peptide-1 receptor (GLP-1-R) and are selective over glucagon receptor (Gluc-R). Specifically provided are GIP analogs with amino acid substitutions introduced to modulate activity for both GIP-R and GLP-1-R and maintain selectivity over Gluc-R.
