Headless compression screws are described. The headless compression screws include first and second ends coupled by a shaft, a first threaded portion positioned proximate the first end that surrounds the shaft and includes s first threads spaced apart from one another at a constant pitch, and a second threaded portion proximate the second end that surrounds the shaft and includes second threads. The second threads are spaced apart from one another at a variable pitch, such that distances between adjacent threads of the second threaded portion decrease as distance from the second end decreases. Methods of reducing a fracture using headless compression screws are also described.