ДЕ АЛЬМЕЙДА Жозе Луиш (PT),ЛИРМОНТ Дэвид Александр (PT),СИЛВА Патрисиу Мануэл Виэйра Араужу Суареш Да (PT)
申请号：
RU2010154173/15
公开号：
RU2010154173A
申请日:
2009.07.29
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. The use of a compound of formula I! ! wherein R1 and R2 are identical or different and denote hydrogen, groups that are hydrolyzed under physiological conditions, or optionally substituted alkanoyl or aroyl X represents a methylene group Y represents O, S or NH n represents 0, 1, 2 or 3 m represents 0 or 1 R3 is a group of pyridine N-oxide according to the formula A, B or C, which is attached as shown unmarked bond: ! where R4, R5, R6 and R7 are the same or different and are hydrogen, alkyl, thioalkyl, alkoxy, aryloxy, thioaryl, alkanoyl, aroyl, aryl, amino, alkylamino, dialkylamino, cycloalkylamino, geterotsikloalkilamino, alkylsulfonyl, arylsulfonyl, halogen, haloalkyl, trifluoromethyl, cyano, nitro or heteroaryl or two or more taken together, R4, R5, R6 and R7 represent aliphatic or heteroaliphatic rings or aromatic or heteroaromatic rings The term "alkyl", including its variant "alk-" in terms such as "alkoxy" and "alkanoyl" means carbon residues, straight or branched, containing from one to six carbon atoms The term "aryl" means a phenyl or naphthyl group The term "heterocycloalkyl" represents a four to eight membered cyclic ring, optionally containing at least one oxygen, sulfur or nitrogen The term "heteroaryl" represents a five or six membered ring containing at least one sulfur, oxygen or nitrogen The term "halogen" represents fluoro, chloro, bromo or iodo and if R4, R5, R6 and R7 represent alkyl or aryl they are optionally substituted by one or more than one hydroxyechinenone
