In order to provide the effective vaccine of confrontation propionibacterium acnes (Propionibacterium acnes) infection, the present invention provides a kind of peptide, the peptide that the peptide is made of specific amino acid is either by the peptide being made up of missing, replacement, insertion or the one or more amino acid derived amino acid sequences from the specific amino acid of addition, the inflammation that the peptide inhibits propionibacterium acnes infection caused by immune response.爲了提供對抗痤瘡丙酸杆菌(Propionibacterium acnes)感染的有效疫苗,本發明提供一種肽,所述肽是由特異性氨基酸序列組成的肽或者是由通過缺失、替換、插入或添加一個或多個氨基酸衍生自所述特異性氨基酸序列的氨基酸序列組成的肽,所述肽通過免疫應答抑制痤瘡丙酸杆菌感染所引起的炎症。