A pharmaceutical composition for improving wound healing is provided. The pharmaceutical composition includes (a) hyaluronic acid or its derivatives, (b) an effective amount of an active ingredient; and optionally (c) pharmaceutically acceptable carriers and/or excipients. In one embodiment, the active ingredient includes vitamin. In another embodiment, the active ingredient includes acexamic acid. In still another embodiment, the pharmaceutical composition can further comprise sorbic acid.本發明提供了一種用於促進傷口癒合之醫藥組合物。此醫藥組合物包含:(a)玻尿酸或其衍生物、(b)有效劑量的一有效活性成分、以及選擇性的(c)醫學上可接受的載劑及/或賦形劑。於一實施例中,有效活性成分包含維生素。於另一實施例中,有效活性成分包含醋氨己酸。於另一實施例中,本發明的醫藥組合還可進一步包含山梨酸。