An environmental sanitizing device (1) comprising a frame (2) housing a reservoir (7) of a disinfectant liquid (3) and supporting a nozzle (4), the nozzle (4) being associated with a generation system (5, 6) of an air flow within which a plurality of disinfectant liquid particles are suspended so as to sanitize a closed environment in which the device (1) can be positioned the nozzle is movable with respect to the frame, and is associated with positioning system (21, 22) controlled by a control unit (100) for the orientation of the nozzle with respect to at least two mutually perpendicular axes (R, A), preferably around a first vertical axis (R) and around a second horizontal axis (A) so as to automatically orient the nozzle in a desired direction with respect to the frame (2) during a sanitization step, the nozzle (4) being coupled with at least one distance detector (L1, L2, L3, L4) able to determine the distance between the nozzle (4) and an obstacle facing the nozzle.