An automated apparatus for the prevention and treatment of the Colony Collapse Disease (CCD) through the administration of nutrients and therapeutic to bee colonies to be treated comprises a box-like container (10) of a material resistant to atmospheric agents which accommodates in its interior at least a first reservoir (9) being liquid-tight fitted with a stirrer (12) and accessible from the outside through a first nozzle (4), an atomizing device (15) of a liquid solution or suspension of nourishment contained in the tank, means for the delivery (2, 1) of the liquid solution or suspension atomized into micrometric drops outside the apparatus, and a control unit (7) programmed for timing the delivery of the solution or suspension to the outside, for the determination of the amount of solution or suspension delivered and for emitting alarm signals in case of malfunctions of the apparatus or reduction of the solution or suspension in a liquid contained in the reservoir (9) below a predetermined level. The apparatus is powered by direct current with the energy supplied by a solar panel (5) located outside of the container and electrically connected to the control unit (7). Further disclosed is a liquid solution or suspension of nutrients that can be delivered in a spray form through the above deceived automated apparatus for the prevention and treatment of the Colony Collapse Disease (CCD). The solution or suspension comprises in a single aqueous solution or suspension of a) tonics and nutritious ingredients, mainly consisting of: milk powder and/or yeasts, sugars and lower organic acids b) natural antioxidants and antiseptics contained in the extracts of one or more aromatic or medicinal plants selected from: Crocus sativus, Pelargonium graveolens, Monarda citriodora, Myristica fragrans, Origanum vulgare and Origanum majorana and c) substances medicinal to bees, selected from thymol, oxalic acid, extracts of Thymus vulgaris, extracts of Aloe arborescens, extracts of