NOUVEAUX DERIVES DE 1-BENZYL-3-HYDROXYMETHYLINDAZOLE ET LEUR UTILISATION DANS LE TRAITEMENT DES MALADIES BASEES SUR L'EXPRESSION DE MCP-1, CX3CR1 ET P40

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专利权人:

AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.

发明人:

GUGLIELMOTTI, ANGELO,FURLOTTI, GUIDO,MANGANO, GIORGINA,CAZZOLLA, NICOLA

申请号：

CA2714436

公开号：

CA2714436C

申请日:

2009.03.05

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present invention relates to novel 1-benzyl-3-hydroxymethylindazolederivatives according to Formula (I) describedin the claims, and to a pharmaceutical composition comprising them, togetherwith a pharmaceutically acceptable vehicle.In addition, the present invention relates to the use of 1-benzyl-3-hydroxymethylindazole derivatives for the preparation of apharmaceutical composition that is active in the treatment of diseases basedon the expression of MCP-1, CX3CR1 and p40, and totheir use in a method for treating or preventing diseases based on theexpression of MCP-1, CX3CR1 and p40.

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