BENATUIL LORENZO,ARGIRIADI MARIA A,MCRAE BRADFORD L,HSIEH CHUNG MING
申请号:
IN201717042831
公开号:
IN201717042831A
申请日:
2017.11.29
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present invention encompasses antagonist anti CD40 antibodies and antigen binding portions thereof. Specifically the invention relates to humanized anti CD40 antibodies. In certain embodiments antibodies of the invention neutralize human CD40 (hCD40) activity. Antibodies or antibody portions of the invention are useful for detecting CD40 and for inhibiting CD40 activity e.g. in a human subject suffering from a disorder in which CD40 activity is detrimental.