PROBLEM TO BE SOLVED: To provide a technology for reducing gastric mucosa disorder when loxoprofen and caffeine are contained.SOLUTION: A medicine composition for common cold capable of reducing gastric mucosa disorder caused by loxoprofen is characterized by including (a) loxoprofen, (b) caffeine and (c) &ge1 kind selected from mequitazine, epinastine and/or fexofenadine.