A locking device (1) with stopper (100) in a receptacle (101) with a collar (102), including a cover (2) which houses a ring (4) provided with notches lower internal equipment (42) in contact with the said collar (102) and external notches (44) cooperating with a groove (22) of the cover (2) in order to secure the said ring (4) to said cover (2), said cover (2) comprising a scored and breakable zone (z1), said ring (4) being formed by a ring (40) is extended by lugs (41) intended to surround the said stopper (100) and provided with at least a bridge (45) which is deformable and separable provided on the opposite side of the said lugs (41) and able to be radially deformed elastically in order to allow the passage of the force of the said collar (102) into the said ring (4) and to be broken in order to allow the removal of the said ring (4) with respect to said collar (102) and then the removal of said stopper (100) of said container (101).
