Zhu, Yunxiang,Cheng, Seng H.,Jiang, Canwen,Avila, Luis Z.
申请号:
HRP20191562
公开号:
HRP20191562T1
申请日:
2019.08.30
申请国别(地区):
HR
年份:
2019
代理人:
摘要:
The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy group to glycoproteins, and oligosaccharide-protein conjugates. Also provided are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-protein conjugate.