UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
发明人:
BADYLAK, STEPHEN F.,DEARTH, CHRISTOPHER LEE,KEANE, TIMOTHY JOSEPH, JR.,TURNER, NEILL JORDON
申请号:
CA2943182
公开号:
CA2943182A1
申请日:
2015.03.20
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Provided are methods for preparing sterilized, gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth substrates. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.