University of Pittsburgh - Of the Commonwealth System of Higher Education
发明人:
Stephen F. Badylak,Christopher Lee Dearth,Timothy Joseph Keane, JR.,Neill Jordon Turner
申请号:
US16238826
公开号:
US20190374683A1
申请日:
2019.01.03
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided are methods for preparing sterilized, gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth substrates. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.