Kyoto Pharmaceutical Industries; Ltd.;KYOTO PHARMA IND
发明人:
申请号:
EP14840281.1
公开号:
EP3040329B1
申请日:
2014.08.29
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Provided is a compound showing a bone formation promoting action (and/or bone resorption suppressive action). A compound of the formula (I) or a pharmacologically acceptable salt: [wherein each substituent is as defined in the DESCRIPTION], has low toxicity, shows good pharmacokinetics, has an action to promote bone formation, and is useful for the prophylaxis or treatment of metabolic bone diseases (osteoporosis, fibrous osteitis (hyperparathyroidism), osteomalacia, Paget's disease that influences the systemic bone metabolism parameter etc.) associated with a decrease in the bone formation ability as compared to the bone resorption capacity.