Takashi Kei Kishimoto,Christopher Fraser,Roberto A. Maldonado
申请号:
US16560419
公开号:
US20200101155A1
申请日:
2019.09.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering MHC Class I-restricted and/or MHC Class II-restricted epitopes of an antigen and immunosuppressants in order to generate tolerogenic immune responses against the antigen, such as the generation of antigen-specific CD8+ regulatory T cells.