Christopher Fraser;Takashi Kei Kishimoto;Roberto A. Maldonado
发明人:
Takashi Kei Kishimoto,Christopher Fraser,Roberto A. Maldonado
申请号:
US13457936
公开号:
US20120276155A1
申请日:
2012.04.27
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering MHC Class I-restricted and/or MHC Class II-restricted epitopes of an antigen and immunosuppressants in order to generate tolerogenic immune responses against the antigen, such as the generation of antigen-specific CD8+ regulatory T cells.