KIM, Sung-Eun,LEE, Sunho,RAJESH, Rengasamy,KANG, Dae Ho,RYU, Hyung Chul,KIM, Jae-Sun,LEE, Sangryul,KIM, Kyong Cheol,RHO, Jin Kyung,LEE, Jae Cheol
申请号:
AU2018379499
公开号:
AU2018379499A1
申请日:
2018.12.06
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present invention provides a novel pyrimidine derivative compound and a salt thereof. The pyrimidine derivative compound effectively inhibits the growth of cancer cells in which c797s-mutated EGFR expression and MET amplification, which are major resistance mechanisms of third generation EGFR anticancer drugs, have occurred, thereby being effectively usable in the treatment of lung cancer.