Richard V. Connors,Kang Dai,John Eksterowicz,Pingchen Fan,Benjamin Fisher,Jiasheng Fu,Kexue Li,Zhihong Li,Lawrence R. McGee,Rajiv Sharma,Xiaodong Wang
申请号:
US12936725
公开号:
US08389533B2
申请日:
2009.04.06
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of CDK4-mediated disorders, such as cancer. The subject compounds are gem-disubstituted or spirocyclic pyridine, pyrimidine and triazine derivatives.