Alistair J. Leigh,Christopher A. Procyshyn,Ernest S.Y. Wong,Christen M. Giandomenico
申请号：
US14668163
公开号：
US20150196494A1
申请日:
2015.03.25
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention provides an oral dosage form for the anti-cancer drug picoplatin comprising a core and a coating, the dosage form being free of redox-active, metal salts. The core of the tablet is a substantially dry powder comprising about 10 to 60 wt % picoplatin wherein the picoplatin is a particulate of less than about 10 microns average particle diameter, about 40-80 wt % of a filler comprising a substantially water-soluble, water-dispersible, or water-absorbing carbohydrate, and an effective amount of up to about 5 wt % of a lubricant. The dosage form can further include a dispersant.
