A nose bleed treatment system for use in treating a patient having a nose bleed uses a nose clip that has a swab adjustment holder disposed on it to moveably hold a bulky or oversized swab within it. The swab can be moved to press against a bleed site in a patient having a bloody nose. A medically effective agent is applied to the bleed site either by applying it to the swap or by using a specially designed spray bottle. In the embodiment using the spray bottle, the bottle has an elongated tip that allows the user to position the tip of the spray bottle proximal to the bleed site. The medically effective agent contains at least one of a clot enhancing agent and a vasoconstricting agent. The agent may contain vitamin K as well as a vasoconstricting agent epinephrine.
