MEYERS, ANN ELIZABETH,WILLIAMSON, ANNA-LISE,RYBICKI, EDWARD PETER,MARGOLIN, EMMANUEL AUBREY,CHAPMAN, ROSAMUND
申请号：
CA3040418
公开号：
CA3040418A1
申请日:
2017.10.13
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to a method for producing a recombinant HIV glycoprotein polypeptide in a plant and to trimeric complexes of the recombinant, plant-produced HIV glycoprotein polypeptide which mimic the native HIV Env complex. The invention also relates to nucleic acids encoding the recombinant polypeptides, expression vectors containing the aforementioned nucleic acids and to pharmaceutical compositions, uses and methods of eliciting an immune response against HIV in a subject using the recombinant polypeptides and trimeric complexes.
