(1-aza-biciklo(3.3.1)non-4-il)-(5-(1H-indol-5-il)-heteroaril)-amini kot holinergični ligandi n-AChR za zdravljenje psihotičnih in nevrodegenerativnih motenj
FREDERIKSEN MATHIAS,FEUERBACH DOMINIK,HURTH KONSTANZE,KOLLER MANUEL,ROY BERNARD LUCIEN
申请号:
SI200631235
公开号:
SI1966208T1
申请日:
2006.12.14
申请国别(地区):
SI
年份:
2012
代理人:
摘要:
The present invention relates to compounds of formula (I) wherein n represents 0, 1, 2, 3, 4 or 5, R represents independent from each other hydroxyl, cyano, nitro, halogen, alkyl, alkoxy alkylcarbonyl, alkoxycarbonyl, alkylamine, dialkylamine, alkylcarbonylamine, alkylcarbamate Y represents one of the following groups: in free base or acid addition salt form, to processes for their production to pharmaceutical compositions comprising them and for use as cholinergic ligands of n-AChR.