(1-Aza-bicyklo[3.3.1]non-4-ylo)-[5-(1H-indol-5-ilo)-heteroarylo}-aminy jako ligandy cholinergiczne receptorów n-AChR do leczenia zaburzeń psychotycznych i neurodegeneracyjnych
FREDERIKSEN, MATHIAS,FEUERBACH, DOMINIK,HURTH, KONSTANZE,KOLLER, MANUEL,ROY, BERNARD LUCIEN
申请号:
PL06840977
公开号:
PL1966208T3
申请日:
2006.12.14
申请国别(地区):
PL
年份:
2012
代理人:
摘要:
The present invention relates to compounds of formula (I) wherein n represents 0, 1, 2, 3, 4 or 5, R represents independent from each other hydroxyl, cyano, nitro, halogen, alkyl, alkoxy alkylcarbonyl, alkoxycarbonyl, alkylamine, dialkylamine, alkylcarbonylamine, alkylcarbamate Y represents one of the following groups: in free base or acid addition salt form, to processes for their production to pharmaceutical compositions comprising them and for use as cholinergic ligands of n-AChR.