Method for preparing acetylcholinesterase inhibitory compound having promnesia effect and 5HT4 serotonergic receptor agonist, and constituent drug composition thereof
Preparation method of acetylcholinesterase inhibitory compound and 5HT4 serotonergic receptor agonist and constituent drug composition thereof. The present invention relates to compounds of formula (I) such as neurogenic enantiomers: In most of the possible meanings, X represents halogen, Y represents an oxygen atom, m, n, r and s all have a value of 1, R represents methyl and R 'represents cycloalkyl. The present invention also includes a method for preparing the above compounds and a pharmaceutical composition constituting them. [Selection figure] Noneアセチルコリンエステラーゼ抑制効果のある化合物及び5HT4セロトニン作動性受容体作動薬の調製方法及びその構成薬剤組成。本発明は神経因性の鏡像異性体などの式(I)の化合物:【化1】に関する。考えられる語義のうちの大半は、Xがハロゲン、Yが酸素原子を表し、m、n、r及びsの値がすべて1であり、Rがメチル、R’がシクロアルキルを表す。また、本発明は上記化合物の調製方法並びにそれらを構成する薬剤組成も含む。【選択図】 なし