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Heterocycle derivatives having TrkA inhibitory activity
专利权人:
Ltd.;Shionogi &; Co.
发明人:
Akira Yukimasa,Kenichiroh Nakamura,Masanao Inagaki,Kazuya Kano,Motohiro Fujiu,Hiroki Yamaguchi,Kayoko Hata,Takatsugu Inoue
申请号:
US15741875
公开号:
US10640495B2
申请日:
2016.07.06
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides a compound having a TrkA inhibitory activity or a pharmaceutically acceptable salt thereof.The present invention relates to a compound represented by Formula (I):wherein -L- is —;C(═;X)—;, or the like, —;Z—; is —;NR5—;, or the like, —;ZA—; is —;NR5A—;, or the like, B is substituted or unsubstituted aromatic carbocyclyl, or the like, Y is a single bond, or the like, the ring C is a substituted or unsubstituted aromatic heterocycle, or the like, R2 is a hydrogen atom, or the like, and the group represented byis a group represented by Formula:or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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